A hard-hitting and timely report on a pervasive threat.
Deadly germs escape from advanced laboratories with alarming and perhaps catastrophic consequences, according to this sobering nonfiction book.
Investigative journalist Young, who’s worked as a reporter and editor for such outlets as USA Today, the Detroit Free Press, and the Atlanta Journal-Constitution, explores lapses, accidents, and disasters at high-containment Biosafety Level 2, 3, and 4 laboratories around the world. They include a 1978 smallpox outbreak at a lab at Britain’s Birmingham University that resulted in the world’s last smallpox death (in which the remorseful lab director committed suicide); a 1979 anthrax release from a Soviet bioweapons lab in Sverdlovsk, which killed dozens of people; several leaks of contaminated wastewater at the U.S. Army’s Fort Detrick biological research institute in 2018, which may have traveled to the nearby town of Frederick, Maryland; a lab tech’s death from a bacterial infection in a San Francisco Veterans Administration medical center; several leaks of a SARS-associate coronavirus from Asian labs in 2003 and 2004, resulting in one death; and the exposure of lab workers to engineered microbes during “gain of function” research that seeks to make pathogens more infectious. A lengthy chapter explores the possibility that the Covid-19 pandemic was caused by a virus that escaped from the Wuhan Institute of Virology. Young dives deeply into how lab safeguards can fail because of equipment breakdowns, leaky pipes, holes in biohazard suits, mislabeled vials, accidental needle sticks, and other circumstances. The book also offers an absorbing account of Young’s own dogged reporting as she visits labs (she once found a high-tech containment-lab door sealed shut with duct tape), pries information out of reluctant officials, and receives tips from anonymous sources. She renders scientific issues in lucid, accessible prose that vividly conveys the insidious nature of potentially lethal microbes: “Other liquid or solid particles were so small they became airborne, spreading on invisible air currents, pushed along by heating and cooling systems, the opening and closing of doors, and the movement of people between rooms and down hallways.” Throughout, Young shows just how perilous infectious-disease research can be.
A hard-hitting and timely report on a pervasive threat.Pub Date: April 25, 2023
ISBN: 9781546002932
Page Count: 352
Publisher: Center Street/Hachette
Review Posted Online: Sept. 22, 2023
Kirkus Reviews Issue: Nov. 1, 2023
Review Program: Kirkus Indie
BOOK REVIEW
PERSPECTIVES
Cogent, well-timed ideas for meeting today’s biggest challenges.
Helping liberals get out of their own way.
Klein, a New York Times columnist, and Thompson, an Atlantic staffer, lean to the left, but they aren’t interrogating the usual suspects. Aware that many conservatives have no interest in their opinions, the authors target their own side’s “pathologies.” Why do red states greenlight the kind of renewable energy projects that often languish in blue states? Why does liberal California have the nation’s most severe homelessness and housing affordability crises? One big reason: Liberal leadership has ensnared itself in a web of well-intentioned yet often onerous “goals, standards, and rules.” This “procedural kludge,” partially shaped by lawyers who pioneered a “democracy by lawsuit” strategy in the 1960s, threatens to stymie key breakthroughs. Consider the anti-pollution laws passed after World War II. In the decades since, homeowners’ groups in liberal locales have cited such statutes in lawsuits meant to stop new affordable housing. Today, these laws “block the clean energy projects” required to tackle climate change. Nuclear energy is “inarguably safer” than the fossil fuel variety, but because Washington doesn’t always “properly weigh risk,” it almost never builds new reactors. Meanwhile, technologies that may cure disease or slash the carbon footprint of cement production benefit from government support, but too often the grant process “rewards caution and punishes outsider thinking.” The authors call this style of governing “everything-bagel liberalism,” so named because of its many government mandates. Instead, they envision “a politics of abundance” that would remake travel, work, and health. This won’t happen without “changing the processes that make building and inventing so hard.” It’s time, then, to scrutinize everything from municipal zoning regulations to the paperwork requirements for scientists getting federal funding. The authors’ debut as a duo is very smart and eminently useful.
Cogent, well-timed ideas for meeting today’s biggest challenges.Pub Date: March 18, 2025
ISBN: 9781668023488
Page Count: 320
Publisher: Avid Reader Press
Review Posted Online: Jan. 16, 2025
Kirkus Reviews Issue: Feb. 15, 2025
BOOK REVIEW
PERSPECTIVES
SEEN & HEARD
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...
A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.
Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”
A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.Pub Date: Jan. 19, 2016
ISBN: 978-0-8129-8840-6
Page Count: 248
Publisher: Random House
Review Posted Online: Sept. 29, 2015
Kirkus Reviews Issue: Oct. 15, 2015
PERSPECTIVES
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