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THE GENETIC STRAND

EXPLORING A FAMILY HISTORY THROUGH DNA

Twists and turns that rival a well-plotted detective story, complete with a surprise ending.

A provocative meditation on the implications of scientific theories about genetic determinism.

Beginning with the National Book Award–winning Slaves in the Family (1998), Ball has written four books (Peninsula of Lies: A True Story of Mysterious Birth and Taboo Love, 2004, etc.) centered in Charleston, S.C., the home base of his father’s family. In his latest, he tries to uncover the truth about his origins with the help of cutting-edge genetic science. He questions whether the carefully preserved records of Ball family genealogy tell the whole truth. When he accidentally discovers nine small packets of hair in the secret drawer of a family heirloom that has recently come into his possession, he decides to submit samples for genetic analysis, along with his own hair and that of two cousins. The hair packets were apparently collected as treasured mementos over a 175-year period ending in the 1850s. Ball takes them to several forensic laboratories, which mainly deal with crime-scene evidence but are also equipped to look at “ancient” hair. Much of the book describes the methodology employed by these labs. Ball also delves into the science of genetics, which adds another dimension to the tale. He is most interested in probing his racial history, and the results he receives are at first glance surprising. This leads him to consult anthropologists who study population migrations by identifying variations in the genotype of people of Asian, African and European descent. His quest to discover more about the origins of his family leads the author to examine deeper questions about the extent to which personal identity may or may not be determined genetically. He wonders whether our reliance on science is perhaps too uncritical.

Twists and turns that rival a well-plotted detective story, complete with a surprise ending.

Pub Date: Nov. 6, 2007

ISBN: 978-0-7432-6658-1

Page Count: 288

Publisher: Simon & Schuster

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: Sept. 1, 2007

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NIGHT

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the...

Elie Wiesel spent his early years in a small Transylvanian town as one of four children. 

He was the only one of the family to survive what Francois Maurois, in his introduction, calls the "human holocaust" of the persecution of the Jews, which began with the restrictions, the singularization of the yellow star, the enclosure within the ghetto, and went on to the mass deportations to the ovens of Auschwitz and Buchenwald. There are unforgettable and horrifying scenes here in this spare and sombre memoir of this experience of the hanging of a child, of his first farewell with his father who leaves him an inheritance of a knife and a spoon, and of his last goodbye at Buchenwald his father's corpse is already cold let alone the long months of survival under unconscionable conditions. 

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the sphere of suffering shared, and in this case extended to the death march itself, there is no spiritual or emotional legacy here to offset any reader reluctance.

Pub Date: Jan. 16, 2006

ISBN: 0374500010

Page Count: 120

Publisher: Hill & Wang

Review Posted Online: Oct. 7, 2011

Kirkus Reviews Issue: Jan. 15, 2006

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WHEN BREATH BECOMES AIR

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...

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A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.

Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.

Pub Date: Jan. 19, 2016

ISBN: 978-0-8129-8840-6

Page Count: 248

Publisher: Random House

Review Posted Online: Sept. 29, 2015

Kirkus Reviews Issue: Oct. 15, 2015

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