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THE SECRET OF LIFE

ROSALIND FRANKLIN, JAMES WATSON, FRANCIS CRICK, AND THE DISCOVERY OF DNA'S DOUBLE HELIX

A brilliant addition to the literature on the history of biological discovery.

A medical historian offers a new history of one of the 20th century’s most significant scientific quests.

The structure of DNA, announced in 1953 by James Watson and Francis Crick, marked the beginning of the spectacular genetics revolution that has continually accelerated since then. There is no shortage of excellent histories, but Markel, a Guggenheim fellow and professor of medicine at the University of Michigan, has written one of the best. After a quick review of the relevant advancements in the 19th century, the author delivers long, satisfying biographies of the leading figures as well as a large supporting cast, including Linus Pauling and John Randall, who directed the biophysics unit at King’s College in London. Markel provides a meticulous account of DNA research by others, as well, and he emphasizes that Watson and Crick made their breakthrough by examining X-ray photographs of DNA crystals. Producing such crystals required extraordinary dexterity, and photographing them demanded acute technical expertise, which often included building X-ray machines from scratch. The X-ray experts were Maurice Wilkins (who shared the Nobel Prize with Watson and Crick) and Rosalind Franklin, recruited in 1950 when Wilkins seemed to be stalled. Nearly every historian in this area explores the intense dislike between Wilkins and Franklin; all, Markel included, deliver reasonable, if differing explanations. Watson famously disparaged her in his 1968 bestseller, The Double Helix (“he transmogrified her into ‘Rosy,’ the one-dimensional archenemy”), but Markel turns up admirers. In the end, Watson and Crick examined X-rays (Franklin’s were better than Wilkins’), built their model, and went down in history. Franklin died in 1958, and the others barely mentioned her in their 30-minute Nobel Prize lectures in 1962. Nowadays, everyone agrees that she was treated badly and that her work—examined without her permission (“one of the most egregious ripoffs in the history of science”)—was essential to the discovery, but during her life, she never expressed resentment.

A brilliant addition to the literature on the history of biological discovery.

Pub Date: Sept. 21, 2021

ISBN: 978-1-324-00223-9

Page Count: 608

Publisher: Norton

Review Posted Online: July 29, 2021

Kirkus Reviews Issue: Aug. 15, 2021

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KILLERS OF THE FLOWER MOON

THE OSAGE MURDERS AND THE BIRTH OF THE FBI

Dogged original research and superb narrative skills come together in this gripping account of pitiless evil.

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Greed, depravity, and serial murder in 1920s Oklahoma.

During that time, enrolled members of the Osage Indian nation were among the wealthiest people per capita in the world. The rich oil fields beneath their reservation brought millions of dollars into the tribe annually, distributed to tribal members holding "headrights" that could not be bought or sold but only inherited. This vast wealth attracted the attention of unscrupulous whites who found ways to divert it to themselves by marrying Osage women or by having Osage declared legally incompetent so the whites could fleece them through the administration of their estates. For some, however, these deceptive tactics were not enough, and a plague of violent death—by shooting, poison, orchestrated automobile accident, and bombing—began to decimate the Osage in what they came to call the "Reign of Terror." Corrupt and incompetent law enforcement and judicial systems ensured that the perpetrators were never found or punished until the young J. Edgar Hoover saw cracking these cases as a means of burnishing the reputation of the newly professionalized FBI. Bestselling New Yorkerstaff writer Grann (The Devil and Sherlock Holmes: Tales of Murder, Madness, and Obsession, 2010, etc.) follows Special Agent Tom White and his assistants as they track the killers of one extended Osage family through a closed local culture of greed, bigotry, and lies in pursuit of protection for the survivors and justice for the dead. But he doesn't stop there; relying almost entirely on primary and unpublished sources, the author goes on to expose a web of conspiracy and corruption that extended far wider than even the FBI ever suspected. This page-turner surges forward with the pacing of a true-crime thriller, elevated by Grann's crisp and evocative prose and enhanced by dozens of period photographs.

Dogged original research and superb narrative skills come together in this gripping account of pitiless evil.

Pub Date: April 18, 2017

ISBN: 978-0-385-53424-6

Page Count: 352

Publisher: Doubleday

Review Posted Online: Feb. 1, 2017

Kirkus Reviews Issue: Feb. 15, 2017

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POEMS & PRAYERS

It’s not Shakespeare, not by a long shot. But at least it’s not James Franco.

A noted actor turns to verse: “Poems are a Saturday in the middle of the week.”

McConaughey, author of the gracefully written memoir Greenlights, has been writing poems since his teens, closing with one “written in an Australian bathtub” that reads just as a poem by an 18-year-old (Rimbaud excepted) should read: “Ignorant minds of the fortunate man / Blind of the fate shaping every land.” McConaughey is fearless in his commitment to the rhyme, no matter how slight the result (“Oops, took a quick peek at the sky before I got my glasses, / now I can’t see shit, sure hope this passes”). And, sad to say, the slight is what is most on display throughout, punctuated by some odd koanlike aperçus: “Eating all we can / at the all-we-can-eat buffet, / gives us a 3.8 education / and a 4.2 GPA.” “Never give up your right to do the next right thing. This is how we find our way home.” “Memory never forgets. Even though we do.” The prayer portion of the program is deeply felt, but it’s just as sentimental; only when he writes of life-changing events—a court appearance to file a restraining order against a stalker, his decision to quit smoking weed—do we catch a glimpse of the effortlessly fluent, effortlessly charming McConaughey as exemplified by the David Wooderson (“alright, alright, alright”) of Dazed and Confused. The rest is mostly a soufflé in verse. McConaughey’s heart is very clearly in the right place, but on the whole the book suggests an old saw: Don’t give up your day job.

It’s not Shakespeare, not by a long shot. But at least it’s not James Franco.

Pub Date: Sept. 16, 2025

ISBN: 9781984862105

Page Count: 208

Publisher: Crown

Review Posted Online: Aug. 15, 2025

Kirkus Reviews Issue: Sept. 15, 2025

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