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SPLENDID SOLUTION

JONAS SALK AND THE CONQUEST OF POLIO

Scientific triumph by a medical hero, described with admiration and lucidity. (Photos, not seen)

A mighty medical event occurred half a century ago, when the curse of polio—of youthful paralysis and suffocating death—was conquered. It was then that the vaccine developed by Dr. Salk was pronounced safe and effective and mass inoculations began.

There was Jenner in the 18th century, Pasteur in the 19th. Add, for the 20th, Jonas Salk (1914–95). Time writer Kluger (Moon Hunters, 1999) tells the story of the able and ambitious young researcher who launched his battle against the awful illness back when Franklin Roosevelt, most prominent among the disease’s many victims, sponsored the National Foundation for Infantile Paralysis (now the March of Dimes) under the direction of his law partner, Basil O’Connor. O’Connor’s name, the palliative treatments of Sister Kenny, or the fearsome contraption, the Iron Lung, may now be largely forgotten—thanks to the efforts of scientists like Salk, who was happily diverted from law or rabbinical studies to City College and NYU Medical School, and then, during WWII, to research on a flu vaccine. Kluger tells the stories of individual victims of polio. He notes the political infighting and describes the establishment of the Pittsburgh lab. He salutes the sacrificial monkeys and mice and recognizes the painstaking task of isolating strains and types of the disease. The science is made accessible, though sometimes it’s freely dramatized, as, for example, in the personification of little pathogens. Salk’s investigations were devoted to the use of killed virus, to be administered by needle. Albert Sabin, depicted as his everlasting nemesis, promoted the use of live virus, given by sugar cube. (Only recently was the Sabin method fully phased out.) Among the first vaccinated: Salk’s lab colleagues, his family, and himself. While Kluger does recall the excitement of the announcement 50 years ago, he scants the inventor’s life story thereafter. Still, in this unabashedly laudatory history, the story of the achievement is a terrific one.

Scientific triumph by a medical hero, described with admiration and lucidity. (Photos, not seen)

Pub Date: Feb. 1, 2005

ISBN: 0-399-15216-4

Page Count: 366

Publisher: Putnam

Review Posted Online: May 19, 2010

Kirkus Reviews Issue: Dec. 15, 2004

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NIGHT

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the...

Elie Wiesel spent his early years in a small Transylvanian town as one of four children. 

He was the only one of the family to survive what Francois Maurois, in his introduction, calls the "human holocaust" of the persecution of the Jews, which began with the restrictions, the singularization of the yellow star, the enclosure within the ghetto, and went on to the mass deportations to the ovens of Auschwitz and Buchenwald. There are unforgettable and horrifying scenes here in this spare and sombre memoir of this experience of the hanging of a child, of his first farewell with his father who leaves him an inheritance of a knife and a spoon, and of his last goodbye at Buchenwald his father's corpse is already cold let alone the long months of survival under unconscionable conditions. 

The author's youthfulness helps to assure the inevitable comparison with the Anne Frank diary although over and above the sphere of suffering shared, and in this case extended to the death march itself, there is no spiritual or emotional legacy here to offset any reader reluctance.

Pub Date: Jan. 16, 2006

ISBN: 0374500010

Page Count: 120

Publisher: Hill & Wang

Review Posted Online: Oct. 7, 2011

Kirkus Reviews Issue: Jan. 15, 2006

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WHEN BREATH BECOMES AIR

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular...

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A neurosurgeon with a passion for literature tragically finds his perfect subject after his diagnosis of terminal lung cancer.

Writing isn’t brain surgery, but it’s rare when someone adept at the latter is also so accomplished at the former. Searching for meaning and purpose in his life, Kalanithi pursued a doctorate in literature and had felt certain that he wouldn’t enter the field of medicine, in which his father and other members of his family excelled. “But I couldn’t let go of the question,” he writes, after realizing that his goals “didn’t quite fit in an English department.” “Where did biology, morality, literature and philosophy intersect?” So he decided to set aside his doctoral dissertation and belatedly prepare for medical school, which “would allow me a chance to find answers that are not in books, to find a different sort of sublime, to forge relationships with the suffering, and to keep following the question of what makes human life meaningful, even in the face of death and decay.” The author’s empathy undoubtedly made him an exceptional doctor, and the precision of his prose—as well as the moral purpose underscoring it—suggests that he could have written a good book on any subject he chose. Part of what makes this book so essential is the fact that it was written under a death sentence following the diagnosis that upended his life, just as he was preparing to end his residency and attract offers at the top of his profession. Kalanithi learned he might have 10 years to live or perhaps five. Should he return to neurosurgery (he could and did), or should he write (he also did)? Should he and his wife have a baby? They did, eight months before he died, which was less than two years after the original diagnosis. “The fact of death is unsettling,” he understates. “Yet there is no other way to live.”

A moving meditation on mortality by a gifted writer whose dual perspectives of physician and patient provide a singular clarity.

Pub Date: Jan. 19, 2016

ISBN: 978-0-8129-8840-6

Page Count: 248

Publisher: Random House

Review Posted Online: Sept. 29, 2015

Kirkus Reviews Issue: Oct. 15, 2015

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